Research on Alpha GPC is very promising, however more large-scale human trials are still needed to fully determine all of the effects it may have in conjunction with HGH. Many individuals interested in life extension have looked at Alpha GPC as a cheap HGH supplement. In other words, if you want your body to naturally produce higher levels of growth hormone secretion, you could add Alpha GPC … [8] Amongst many athletic types, alpha GPC for bodybuilding has been showing promise in the areas of increased growth hormone release due to its cholinergic properties. Physicians in Europe have prescribed this compound to patients who show symptoms of age-related memory loss. The mechanics of a GPC is that it stops satmostain the enzyme that shuts down HGH so it allows more of what you have to work more efficiently not making more in your body. One study showed that when Alpha GPC 600 mg is ingested orally 90 minutes before exercise, it lead to a 44-fold increase in HGH levels compared to only a 2.6 increase with the same exercise and a placebo. Can You Compare Them? Intense athletic activity and weight lifting can increase HGH secretions, but the effects begin to taper off after the age of 30 as well. HGH has a positive effect on fat burning and muscle building, helping to naturally increase the body’s metabolism. Levels of growth hormone increased significantly in the A-GPC group (0.19 to 8.4 ng/mL) compared to the placebo group (1.9 to 5.0 ng/mL). Alpha-GPC is a hormone secretoguage (booster) that affects the natural release of HGH by the pituitary gland. In a double-blinded, randomized, placebo-controlled crossover study performed at Ritsumeikan University in Kyoto, Japan, researchers gave a group of men, average age 25, a single dose of A-GPC and observed changes in serum choline, human growth hormone (HGH), and markers of fat oxidation, free fatty acids (FFAs), and ketone bodies. More recently, studies published in 2008 and 2012 have found that Alpha GPC increases human growth hormone secretion in the brain. Alpha GPC increases core strength since the neurotransmitter acetylcholine activates muscle contraction, providing more explosive force to your training. That translates into more effective fat burning caused by workout. Your physician can explain any possible risks as well as side effects that may be associated with higher HGH levels based on your personal situation and history. Its potential is especially appreciated by athletes and individuals seeking to develop a muscular figure. Alpha GPC, Growth Hormone, and Life Expectancy Should we be concerned??? Thanks! One of the first things it does is to increase the availability of stored Acetylcholine within your neurons. These athletes see the effects that increasing the amounts of this powerful substance can have on their ability to quickly increase lean muscle mass and strength. Since Alpha GPC enhances the production of this neurotransmitter, it is believed that this is the mechanism by which it boosts levels of growth hormone in the body. The aim of this study was to investigate acute physiologic responses to a single intake of GPC. * Consuming Alpha GPC before exercise may improve muscular power output. HGH is responsible for stimulating cell repair, reproduction and growth. ALPHA GPC provides a bodybuilder with two major benefits to create muscle growth. It is responsible for numerous functions in the body, including boosting muscle mass and removing fatty acids from fat cells. If you are interested in increasing your body’s growth hormone secretion without turning to HGH, then Alpha GPC is a viable option. Glycerophosphocholine may also be used as a hormone secretogauge. A pilot study indicated that a 600 mg dose of alpha GPC, taken 90 minutes before bench pressing, increased power by 14%. [9] Alpha GPC has been shown to double GH production after exercise. HGH is generally only legally available from pharmacies with a prescription from a medical doctor. In a study performed on eight healthy male subjects, the ones who ingested 1000 mg of GPC showed increases in growth hormone secretion and fat oxidation, while subjects who took the placebo did not display these results. This suggests that subcutaneous administration is not necessary and the benefits for HGH can be achieved by taking Alpha GPC orally. Several studies have demonstrated Alpha GPC’s potential perks, and there does not appear to be the same type of side effects or risks that are associated with HGH. There is a growing body of research that assess the effect of alpha-GPC on growth hormone secretion by the pituitary gland. A Japanese study examined the effect of a single dose of Alpha GCP on growth hormone secretion in healthy young males (10). This was followed up with a 2012 study in the venerable journal Nutrition that found Alpha GPC increases secretion of HGH as well as increases fat oxidation. Interest in alpha-GPC as a supplement primarily stems from its ability to provide choline to the brain with a considerably higher bioavailability than other choline donors such as phosphatidylcholine. Alpha GPC raises GH levels by stimulating the release of Growth Hormone Releasing Hormone (GHRH). Serotonin 4. Also Doctors do not subscribe this unless certain qualifiable parameters are met through extensive tests. Cholinergic neurotransmission in the hippocampus of aged rats: influence of L-alpha-glycerylphosphorylcholine treatment. Proper dosage is dependent on many different factors, and it is recommended that you speak with your doctor before beginning any new supplements to help determine the best dosage for your needs. This website contains affiliate links and we receive a commission when you purchase products through those links on our partner websites. Alpha-GPC is a nootropic that has gained the attention of the masses due to its strong memory-enhancing benefits. Alpha GPC intake can also increase the production of the growth hormone within the body and thus, athletes around the work use Alpha GPC supplements to enhance their overall power output. Amongst many athletic types, alpha GPC for bodybuilding has been showing promise in the areas of increased growth hormone release due to its cholinergic properties. Before taking Alpha GPC to increase Human Growth Hormone levels, it would be best to speak to a doctor. Increased Growth Hormone and Fat Burning. Alpha-GPC supports the whole nervous system by boosting acetylcholine and cholinergic activity. Alpha-GPC Alpha-glycerophosphocholine (Alpha-GPC or α-GPC) is a cholinergic compound that is used for its cognitive-promoting properties, and to enhance power output in athletes. 2014, Govoni S, Battaini F, Lucchi L, Pascale A, Trabucchi M. PKC translocation in rat brain cortex is promoted in vivo and in vitro by alpha-glycerylphosphorylcholine, a cognition-enhancing drug. Alpha-GPC is a non-tropic cholinergic supplement that can be used before training to improve sports performance. 2012. Due to the extensive benefits that can accrue from higher growth hormone levels, this link has generated a lot of interest in the supplement community. 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